Parkinson Disease

A brief overview

Certain neurons in the part of the human brain called substantia nigra are responsible for producing a chemical called dopamine which aids in controlled muscle movement. The death of these neurons leads to a deficiency of dopamine further leading to erratic muscle movement. An early symptom of Parkinson’s is a resting tremor, i.e. a small tremor in the affected body part when it is not performing action. As the disease progresses, it leads to muscle stiffness and rigidity making everyday activities difficult to perform. Though we know that the lack of dopamine is the primary cause for Parkinson’s, it is not known what exactly causes the death of dopamine-producing neurons. Parkinson’s UK, a research and support charity, is funding more than 40 different studies to answer this question.

 articles by Shrideep Murthy 

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